Cd2-2A-CreERT2

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Strain Information

  • Catalog Number ASKI-18017
  • Model Name Cd2-2A-CreERT2
  • Strain Name C57BL/6J-Cd2em1(2A-CreERT2-WPRE-pA)/Asc
  • Mutation Type Knock-in
  • GENE Synonyms Ly37, LFA-2, Ly-37
  • Human Orthologs CD2
  • Emsamble ID ENSMUSG00000027863
  • MGI ID 88320
  • NCBI ID 12481
  • Background C57BL/6J
  • Coat Color Black
  • Mutation Type Knock-in
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SKU :
ASKI-18017
Catalog # :
ASKI-18017
Availability :
Mouse
  • Description
  • Research Application
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Model Description

A 2A-CreERT2-WPRE-pA coexpression cassette is inserted before the stop codon of mouse Cd2 gene via homologous recombination to establish a tamoxifen inducible Cd2-CreERT2 tool stain. This strain can be used to knockout target gene in T cells and B cells after tamoxifen treatment when crossed with mice which carry loxp sites flanking target gene.

Validation Data

landingpage-aski-18017-Cd2-2A-CreERT2-ki-mouse-1

Figure 1.  The result shows that expression pattern of RFP in T cells of Cd2-(2A-CreERT2-WPRE-pA); RFP.

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