C57BL/6J-Cd2em1(2A-CreERT2-WPRE-pA)Asc

SKU :

ASKI-18017

Catalog # :

ASKI-18017

Availability :

Mouse

C57BL/6J-Cd2em1(2A-CreERT2-WPRE-pA)Asc

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Strain Information

Catalog Number ASKI-18017
Model Name Cd2-(2A-CreERT2-WPRE-pA)
Strain Name ASKI-18017
Mutation Type Knock-in
GENE Synonyms Ly37; LFA-2; Ly-37
Human Orthologs CD2
Emsamble ID ENSMUSG00000027863
MGI ID 88320
NCBI ID 12481
Background C57BL/6J
Coat Color Black
Mutation Type Knock-in

Description

A 2A-CreERT2-WPRE-pA coexpression cassette is inserted befor the stop codon of mouse Cd2 gene via homologous recombination to establish a tamoxifen inducible Cd2-CreERT2 tool stain. This strain can be used to knockout target gene in T cells and B cells after tamoxifen treatment when crossed with mice which carry loxp sites flanking target gene.

Research Application

Immunotherapy

Availability

Mouse