C57BL/6J-Lyz2em1(2A-CreERT2-WPRE-pA)Asc

SKU :

ASKI-18018

Catalog # :

ASKI-18018

Availability :

Mouse

C57BL/6J-Lyz2em1(2A-CreERT2-WPRE-pA)Asc

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Strain Information

Catalog Number ASKI-18018
Model Name Lyz2-(2A-CreERT2-WPRE-pA)
Strain Name ASKI-18018
Mutation Type Knock-in
GENE Synonyms Lys; Lzm; Lzp; Lysm; Lyzs; Lyzf2; Lzm-s1; AI326280
Emsamble ID ENSMUSG00000069516
MGI ID 96897
NCBI ID 17105
Background C57BL/6J
Coat Color Black
Mutation Type Knock-in

Description

A 2A-CreERT2-WPRE-pA coexpression cassette is inserted befor the stop codon of mouse Lyz2 gene via homologous recombination to establish a tamoxifen inducible Lyz2-CreERT2 tool stain. This strain can be used to knockout target gene in Lyz2+ cells after tamoxifen treatment when crossed with mice which carry loxp sites flanking target gene.

Research Application

Immunotherapy

Availability

Mouse