Cd8a-(V5-IRES-Akaluc-2A-EGFP) - Other Gene Edited Mouse Models (KO, CKO) - Mouse Repository - Animal Models - Research

SKU :
ASKI-18030
Catalog # :
ASKI-18030
Availability :
Mouse
Using CRISPR gene editing technology, a V5-IRES-Akaluc-2A-EGFP expression cassette was inserted before the stop codon TAA of mouse Cd8a gene to establish a multi-labeled Knock-in model with V5, Akaluc luciferase and EGFP fluorescent protein. Akaluc is a novel luciferase that produces up to 1,000 times as bright as light emitted by existing systems by feeding or injecting a synthetic luciferin compound called AkaLumine-HCl, which is better able to penetrate the blood-brain barrier than d-luciferi .....
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Strain Information
  • Catalog Number ASKI-18030
  • Model Name Cd8a-(V5-IRES-Akaluc-2A-EGFP)
  • Strain Name C57BL/6J-Cd8aem1(V5-IRES-Akaluc-2A-EGFP)Asc
  • GENE Synonyms Ly-2, Ly-35, Ly-B, Lyt-2
  • Human Orthologs CD8A
  • Emsamble ID ENSMUSG00000053977
  • MGI ID 88346
  • NCBI ID 12525
  • Backgound C57BL/6J
  • Coat Color Black
Description
Using CRISPR gene editing technology, a V5-IRES-Akaluc-2A-EGFP expression cassette was inserted before the stop codon TAA of mouse Cd8a gene to establish a multi-labeled Knock-in model with V5, Akaluc luciferase and EGFP fluorescent protein. Akaluc is a novel luciferase that produces up to 1,000 times as bright as light emitted by existing systems by feeding or injecting a synthetic luciferin compound called AkaLumine-HCl, which is better able to penetrate the blood-brain barrier than d-luciferin is.
Research Application
Immunotherapy
Availability
Mouse
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