H11-(pThy1-PSEN1-IRES-tdTomato) - Other Gene Edited Mouse Models (KO, CKO) - Mouse Repository - Animal Models - Research

SKU :
ASKI-18049
Catalog # :
ASKI-18049
Availability :
Mouse
A Thy1 promoter-PSEN1-IRES-tdTomato-WPRE-polyA cassette was knocked into the Igs2 locus (Hipp11 or H11; an intergenic region on chromosome 11 [cytoband A1 at ~3cM between the Eif4enif1 and Drg1 loci] reported to support high-level global gene expression in conjunction with the CAG (CAGGS) promoter and a higher rate of mitotic/interchromosomal recombination compared to Gt(ROSA)26Sor) by CRISPR/Cas9 gene editing technology.
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Strain Information
  • Catalog Number ASKI-18049
  • Model Name H11-(pThy1-PSEN1-IRES-tdTomato)
  • Strain Name C57BL/6-Igs2em1(pThy1-PSEN1-IRES-tdTomato-WPRE-pA)Asc
  • Backgound C57BL/6J
  • Coat Color Black
Description
A Thy1 promoter-PSEN1-IRES-tdTomato-WPRE-polyA cassette was knocked into the Igs2 locus (Hipp11 or H11; an intergenic region on chromosome 11 [cytoband A1 at ~3cM between the Eif4enif1 and Drg1 loci] reported to support high-level global gene expression in conjunction with the CAG (CAGGS) promoter and a higher rate of mitotic/interchromosomal recombination compared to Gt(ROSA)26Sor) by CRISPR/Cas9 gene editing technology.
Research Application
Immunotherapy
Availability
Mouse
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