R26-(EZH2)

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Strain Information

Catalog Number ASKI-18053
Model Name R26-(EZH2)
Strain Name C57BL/6J-Gt(ROSA)26Sor^{em1(CAG-LSL-EZH2-IRES-luciferase-2A-tdTomato)Asc}
Human Orthologs EZH2
Background C57BL/6J
Coat Color Black

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SKU :

ASKI-18053

Catalog # :

ASKI-18053

Availability :

Mouse

Description
Research Application
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A SA-2xpolyA-CAG-Loxp-Stop-Loxp-human EZH2 cDNA-IRES-luciferase-2A-tdTomato-wpre-polyA cassette was knocked into the mouse Rosa26 locus by CRISPR/Cas9 gene editing technology. This strain of mice can be mated with mice expressing Cre recombinase so that human EZH2 could be expressed after exposure to Cre recombinase.

Immunotherapy