R26-(CAG-LSL-EML4-ALK(F1174L)-luciferase-tdTomato) - Other Gene Edited Mouse Models (KO, CKO) - Mouse Repository - Animal Models - Research

SKU :
ASKI-190010
Catalog # :
ASKI-190010
Availability :
Mouse
A SA-2xpolyA-CAG-LSL-EML4-ALK(F1174L)-IRES-Luciferase-2A-tdTomato-WPRE-polyA cassette was inserted at the Rosa26 locus using CRISPR gene editing technology. When bred to a strain expressing Cre recombinase under control of various tissue specific promoters, Cre recombination deletes the LSL cassette and allows the expression of the EML4-ALK(F1174L) protein.
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Strain Information
  • Catalog Number ASKI-190010
  • Model Name R26-(CAG-LSL-EML4-ALK(F1174L)-luciferase-tdTomato)
  • Strain Name C57BL/6J-Gt(ROSA)26Sorem1(SA-2xpolyA-CAG-LSL-EML4-ALK(F1174L)-IRES-luciferase-2A-tdTomato)Asc
  • Emsamble ID ENSMUSG00000086429
  • MGI ID 104735
  • NCBI ID 14910
  • Backgound C57BL/6J
  • Coat Color Black
Description
A SA-2xpolyA-CAG-LSL-EML4-ALK(F1174L)-IRES-Luciferase-2A-tdTomato-WPRE-polyA cassette was inserted at the Rosa26 locus using CRISPR gene editing technology. When bred to a strain expressing Cre recombinase under control of various tissue specific promoters, Cre recombination deletes the LSL cassette and allows the expression of the EML4-ALK(F1174L) protein.
Research Application
Immunotherapy
Availability
Mouse
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