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Strain Information

  • Catalog Number ASKI-190011
  • Model Name Slc17a6-CreERT2
  • Strain Name C57BL/6-Slc17a6em2(CreERT2)/Asc
  • Mutation Type Knock-in
  • GENE Synonyms DNPI, Vglut2, 2900073D12Rik
  • Human Orthologs SLC17A6
  • Emsamble ID ENSMUSG00000030500
  • MGI ID 2156052
  • NCBI ID 140919
  • Background C57BL/6
  • Coat Color Black
  • Mutation Type Knock-in
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This tamoxifen-inducible Slc17a6-CreERT2 tool mouse model was established by inserting a 2A-CreERT2-WPRE-polyA co-expression cassette into the stop codon of Slc17a6 gene.

Validation Data


Figure 1: Expression Pattern of Tomato in Slc17a6-CreERT2 +/-; R26- tdTomato+/- mice.

CreERT2-mediated recombination in excitatory glutamatergic neuron cell bodies of Slc17a6-CreERT2+/-; R26-tdTomato+/- mice. Slc17a6-CreERT2 mice may be used to generate conditional mutations for studying gain-or-loss of function and/or fate mapping related to glutamatergic neurons. 

Tool mice