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Krt14-CreERT2

Krt14-CreERT2

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Strain Information

Catalog Number ASKI-190024
Model Name Krt14-CreERT2
Strain Name C57BL/6-Krt14^{em2(CreERT2-Wpre-polyA)/Asc}
GENE Synonyms Cytokeratin 14, epidermolysis bullosa simplex, Dowling-Meara, Koebner, K14, Krt-1.14, Krt1-14
Human Orthologs KRT14
Emsamble ID ENSMUSG00000045545
MGI ID 96688
NCBI ID 16664
Background C57BL/6
Coat Color Black

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SKU :

ASKI-190024

main product photo

Catalog # :

ASKI-190024

Availability :

Mouse

Description
Research Application
Related Products

A CreERT2-Wpre-polyA expression cassette was knocked into initiation codon ATG site of the Krt14 gene via CRISPR/Cas mediated recombination.

Validation Data

Figure 1: CreERT2-mediated recombination in Skin, Tongue & Esophagus of Krt14 CreERT2+/-; R26 tdTomato+/- mice.

A. Krt14-CreERT2+/- ; Rosa26 tdTomato+/- ; Tamoxifen

B. Krt14-CreERT2+/-; Rosa26 tdTomato+/-

C. Rosa26 tdTomato+/-

landingpage-aski-190024-Krt14-CreERT2-ki-mouse-2

Figure 2: Confocal images showing expression of tdTomato in Skin, Tongue & Esophagus of Krt14 CreERT2+/-; R26 tdTomato +/- mice.

A. Krt14-CreERT2+/- ; Rosa26 tdTomato+/- ; Tamoxifen

B. Krt14-CreERT2+/-; Rosa26 tdTomato+/-

C. Rosa26 tdTomato+/-

Cre recombinase tool