Kras-(LSL-G12D) - Other Gene Edited Mouse Models (KO, CKO) - Mouse Repository - Animal Models - Research

SKU :
ASKI-190003
Catalog # :
ASKI-190003
Availability :
Mouse
Using CRISPR/Cas9 technology, exon2 of Kras were replaced by loxp-stop-loxp and exon2 containing G12D. When crossed with a Cre recombinase-expressing strain, this strain is useful in studies of cancer and development.
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Strain Information
  • Catalog Number ASKI-190003
  • Strain Name C57BL/6-Krasem4(LSL-G12D)Asc
  • Mutation Type Knock-in
  • GENE Synonyms Ki-ras, K-ras, Kras2, Kras-2
  • Human Orthologs KRAS
  • Emsamble ID ENSMUSG00000030265
  • MGI ID 96680
  • NCBI ID 16653
  • Coat Color Black
  • Mutation Type Knock-in
Description

Using CRISPR/Cas9 technology, exon2 of Kras were replaced by loxp-stop-loxp and exon2 containing G12D. When crossed with a Cre recombinase-expressing strain, this strain is useful in studies of cancer and development.

Research Application
cancer research
Availability
Mouse
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