Are you looking to further your preclinical studies and begin your in vivo efficacy, safety, and toxicity experiments? Applied StemCell now supplies research-ready humanized PBMC and CD34+ reconstruction mouse models ideal for infectious disease, gene therapy, hematopoiesis, drug target, and immunogenicity studies. Our humanized models are generated using our M-NSG immunodeficient mice through the injection of healthy human donor peripheral blood mononuclear cells (PBMCs) or CD34+ hematopoietic stem cells (HSCs). After a few weeks of reconstruction following the injection of PBMCs or CD34+ HSCs, the mice develop a human-like immune system and are ready to be shipped.
Shipping from the US facility. Pre-screenned donor, available for further information upon request.
Base Strain: M-NSG
Lifespan: Short-term approx. 3 month
Humanized PBMC and CD34+ Mouse Models - Mouse Repository - Animal Models - Research | ASC (appliedstemcell.com)
Study-ready cohorts of hu-PBMC humanized mice are provided upon request. We can ship to your institution or for enrollment in customized drug/antibody efficacy studies executed by our In Vivo Assay Services team.
Shipment is for the US only.
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