Cardiomyocyte Differentiation Service Details
- Standard
- Fully Customizable Service - Inquire
Standard Packaging:
- Ship 1-2 million iPS cells (1-2 cryovials; 1 million cells/vial); OR
- With pathogen and SARS-CoV-2 test results
- Optional Pathogen Testing Service is available
- With pathogen and SARS-CoV-2 test results
- Select one of our Control iPS Cell Lines; OR
- Let ASC generate your iPSCs from your human or non-human samples
Standard Deliverables:
- Cardiomyocytes differentiated from iPSCs; options available for quantity (Ex. small scale:2 million differentiated cells; medium scale: 2-10 million differentiated cells; large scale: 10-100 million cells).
- QC data: Antibody staining (cTnT, alpha-SMA) and video of beating differentiated cells (before cryopreservation), recovery, and mycoplasma tests.
- Milestone updates/ reports
Standard Workflow and Timeline:
| Service |
| iPSC Recovery and Expansion |
| Pathogen Screening (Optional Add-On) |
| Directed differentiation to cardiomyocyte |
| QC: Antibody staining (cTnT, SMA); video (beating cells); recovery test |
Timeline: 2 weeks
Applications:
- Disease Modeling
- In vitro drug testing and cardiotoxicity screening
- Transplantation research
- Study approaches to regenerative medicine
Video of Beating Cardiomyocytes Differentiated from a Control iPSC Line
The videos seen on the top of the page show beating, cardiomyocytes that were differentiated from an integration-free, control human iPSC line. The cardiomyocytes were on day 3 of recovery after cryopreservation (cryopreserved on day 10 of post-differentiation). The videos were taken by bright-field microscopy at 20x magnification.