Applied StemCell has developed an efficient integration-free method to differentiate high-quality natural killer cells (NK cells) from human iPSCs. The differentiated NK cells recapitulate the phenotype and functional parameters of primary and in vivo NK cells.
We provide NK cells differentiated from an integration-free, control human iPSC line (ASE-9211), reprogrammed from fibroblasts of an African-American male donor. These cryopreserved, high-purity cells express high levels of NK cell biomarkers, CD56 and CD45.
Flow Cytometry Analysis - Supporting Data
Figure 1. Flow cytometry analysis of ASE-9708 iPSC-derived natural killer (NK) cells for NK biomarkers. The NK cells derived from Applied StemCell’s control iPSC line (ASE-9211) were stained with NK cell markers, CD3, CD16, CD314, CD226, and CD56.