PD-1 & CD3E

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Strain Information

  • Catalog Number ASHU-18021
  • Model Name PD-1 & CD3E
  • Strain Name C57BL/6-Pdcd1em1(hPDCD1) Cd3eem1(hCD3E)/Asc
  • Mutation Type Humanized
  • GENE Synonyms Ly101, CD3, T3e, AI504783, CD3epsilon
  • Human Orthologs PDCD1, CD3E
  • Emsamble ID ENSMUSG00000026285, ENSMUSG00000032093
  • MGI ID 104879, 88332
  • NCBI ID 18566, 12501
  • Background C57BL/6
  • Coat Color Black
  • Mutation Type Humanized
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  • Description
  • Research Application
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This PD-1 and CD3e double knockin strain is established by crossing PD-1-HU and CD3e-HU mice together. These double double knockin mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.
Immunotherapy, cancer research, drug screening