CTLA4 & 4-1BB

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Strain Information

  • Catalog Number ASHU-18020
  • Model Name CTLA4 & 4-1BB
  • Strain Name C57BL/6 - Ctla4em1(hCTLA4) Tnfrsf9em1(hTNFRSF9) /Asc
  • Mutation Type Humanized
  • GENE Synonyms Cd152, Ly-56, Ctla-4, 4-1BB, A930040I11Rik, Cd137, CDw137, ILA, Ly63
  • Human Orthologs CTLA4, TNFRSF9
  • Emsamble ID ENSMUSG00000026011, ENSMUSG00000028965
  • MGI ID 88556, 1101059
  • NCBI ID 12477, 21942
  • Background C57BL/6
  • Coat Color Black
  • Mutation Type Humanized
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  • Description
  • Research Application
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This CTLA4 and 4-1BB double knockin strain is established by crossing CTLA4-HU and 4-1BB-HU mice together. These double double knockin mouse models can be useful for evaluating the efficacy of potential immunotherapy drug combinations.
Immunotherapy, cancer research, drug screening