APOE2 - Immune Checkpoint Mouse Models - Mouse Repository - Animal Models - Research

SKU :
ASHU-190013
Catalog # :
ASHU-190013
Availability :
Mouse
Humanized Strategy Validation Data Figure 1. Genotyping of WT, KO &  Humanized mice by PCR. Primer P1/2 Wild type = 342 bp Primer P3/4 mutant = 332 bp M: 100bp Plus DNA ladder. Figure 2. Western blot analysis of  APOE2  protein from WT, KO & Humanized mice.  APOE anti-body: Sc-13521 (santa cruz) Validate Human APOE Expression by Western Blot KO: Apoe knockout mouse sample; hAPOE2 : humanized APOE2 mouse sample (ASHU-190013); hAPOE3 : humanized APOE3 mou .....
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Strain Information
  • Catalog Number ASHU-190013
  • Model Name APOE2
  • Strain Name C57BL/6J - Apoetm4(hAPOE2)ASC
  • Mutation Type Humanized
  • GENE Synonyms Apo-E; AI255918
  • Human Orthologs APOE
  • Emsamble ID ENSMUSG00000002985
  • MGI ID 88057
  • NCBI ID 11816
  • Backgound C57BL/6J
  • Coat Color Black
  • Mutation Type Humanized
Description

Humanized Strategy

Landingpage-ASHU-190013-APOE2-HU-ICPMouse-1


Validation Data

Landingpage-ASHU-190013-APOE2-HU-ICPMouse-2

Figure 1. Genotyping of WT, KO &  Humanized mice by PCR. Primer P1/2 Wild type = 342 bp Primer P3/4 mutant = 332 bp M: 100bp Plus DNA ladder.

Landingpage-ASHU-190013-APOE2-HU-ICPMouse-3

Figure 2. Western blot analysis of  APOE2  protein from WT, KO & Humanized mice.  APOE anti-body: Sc-13521 (santa cruz)

Validate Human APOE Expression by Western Blot

Landingpage-ASHU-190013-APOE2-HU-ICPMouse-4

KO: Apoe knockout mouse sample; hAPOE2 : humanized APOE2 mouse sample (ASHU-190013); hAPOE3 : humanized APOE3 mouse sample (ASHU-190003); hAPOE4 : humanized APOE4 mouse sample (ASHU-190002); WT: wild type mouse sample; M: marker.

Research Application
Immunotherapy
Availability
Mouse
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