PD-L1 & GITR - Immune Checkpoint Mouse Models - Mouse Repository - Animal Models - Research

SKU :
ASHU-190015
Catalog # :
ASHU-190015
Availability :
Mouse
This PD-L1 and GITR double Knock-in strain is established by crossing PD-L1-HU and GITR-HU mice together. These double double Knock-in mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.
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Strain Information
  • Catalog Number ASHU-190015
  • Model Name PD-L1 & GITR
  • Strain Name C57BL/6J - Cd274em1(hPD - L1)Tnfrsf18em1(hTNFRSF18)/Asc
  • Mutation Type Humanized
  • GENE Synonyms B7h1, Pdl1, Pdcd1l1,Pdcd1lg1, A530045L16Rik; AITR, Gitr
  • Human Orthologs CD274; TNFRSF18
  • Emsamble ID ENSMUSG00000016496; ENSMUSG00000041954
  • MGI ID 1926446; 894675
  • NCBI ID 60533;21936
  • Backgound C57BL/6J
  • Coat Color Black
  • Mutation Type Humanized
Description

This PD-L1 and GITR double Knock-in strain is established by crossing PD-L1-HU and GITR-HU mice together. These double double Knock-in mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.

Research Application
Immunotherapy
Availability
Mouse
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