LAG3 & CTLA4 - Immune Checkpoint Mouse Models - Mouse Repository - Animal Models - Research

SKU :
ASHU-190018
Catalog # :
ASHU-190018
Availability :
Mouse
This LAG3 and CTLA4 double Knock-in strain is established by crossing LAG3-HU and CTLA4-HU mice together. These double double Knock-in mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.
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Strain Information
  • Catalog Number ASHU-190018
  • Model Name LAG3 & CTLA4
  • Strain Name B6.129 - Lag3tm1(hLAG3)Ctla4em1(hCTLA4)/Asc
  • Mutation Type Humanized
  • GENE Synonyms Ly66, CD223, LAG-3; Cd152, Ly-56, Ctla-4
  • Human Orthologs LAG3; CTLA4
  • Emsamble ID ENSMUSG00000030124; ENSMUSG00000026011
  • MGI ID 106588; 88556
  • NCBI ID 16768; 12477
  • Backgound C57BL/6J
  • Coat Color Black
  • Mutation Type Humanized
Description

This LAG3 and CTLA4 double Knock-in strain is established by crossing LAG3-HU and CTLA4-HU mice together. These double double Knock-in mouse models can be useful for evalueting the efficacy of potential immunotherapy drug combinations.

Research Application
Immunotherapy
Availability
Mouse
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