IL18BP

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Strain Information

  • Catalog Number ASHU-210039
  • Model Name IL18BP
  • Strain Name C57BL/6-Il18bpem1(hIL18BP)/Asc
  • Mutation Type Humanized
  • GENE Synonyms MC54L, Igifbp, IL-18BP
  • Human Orthologs IL18BP
  • Emsamble ID ENSMUSG00000070427
  • MGI ID 1333800
  • NCBI ID 16068
  • Background C57BL/6
  • Coat Color Black
  • Mutation Type Humanized
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ASHU-210039
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ASHU-210039
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  • Description
  • Research Application
  • Related Products

The endogenous mice Il18bp gene was replaced by human IL18BP gene.

Validation Data

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Figure1. Detection of IL18BP expression in thymus and liver by RT-PCR. 

Wild type: only one band at 354 bp with primers F1/R1 (mIl18bp);Heterozygous: one band at 354 bp with primers F1/R1 (mIl18bp) and one band at 220 bp with primers F2/R2 (hIL18BP); Abbr.. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.

landingpage-ashu-210039-IL18BP-hu-icpmouse-2

Figure 2. Detection of IL18BP expression in thymus and liver by RT-PCR. 

Wild type: only one band at 354 bp with primers F1/R1(mIl18bp); Homozygous: only one band at 220 bp with primers F2/R2(hIL18BP);  Abbr. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.

landinpage-ashu-210039-IL18BP-hu-icpmouse-3

Figure 3. Detection of hIL18BP expression in serum by ELISA. 

Abbr. HO, homozygous; HE, heterozygous; WT, wild type.

laningpage-ashu-210029-IL18BP-hu-icpmouse-4

Figure 4. Detection of mIL18BP expression in serum by ELISA. 

Abbr. HO, homozygous; HE, heterozygous; WT, wild type.

landingpage-ashu-210039-IL18BP-hu-icpmouse-5

Figure 5. Detection of hIL18BP expression in serum by ELISA (n=3). 

Abbr. HO, homozygous; HE, heterozygous; WT, wild type.

landingpage-ashu-210039-IL18BP-hu-icpmouse-6

Figure 6. Detection of mIL18BP expression in serum by ELISA.

Abbr. HO, homozygous; HE, heterozygous; WT, wild type.

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