PD-L1 & CD40

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Strain Information

  • Catalog Number ASHU-18024
  • Model Name PD-L1 & CD40
  • Strain Name C57BL/6-Cd274em1(hPD - L1) Cd40em1(hCD40)/Asc
  • Mutation Type Humanized
  • GENE Synonyms B7h1, Pdl1, Pdcd1l1, Pdcd1lg1, A530045L16Rik, IGM, p50, Bp50, GP39, IMD3, TRAP, HIGM1, T-BAM, Tnfrsf5, AI326936
  • Human Orthologs CD274, CD40
  • Emsamble ID ENSMUSG00000016496, ENSMUSG00000017652
  • MGI ID 1926446, 88336
  • NCBI ID 60533, 21939
  • Background C57BL/6
  • Coat Color Black
  • Mutation Type Humanized
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  • Description
  • Research Application
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This PD-L1 and CD40 double knockin strain is established by crossing PD-L1-HU and CD40-HU mice together. These double double knockin mouse models can be useful for evaluating the efficacy of potential immunotherapy drug combinations.
Immunotherapy, cancer research, drug screening