PD-1 & PD-L1 - Immune Checkpoint Mouse Models - Mouse Repository - Animal Models - Research

SKU :
ASHU-00100
Catalog # :
ASHU-00100
Availability :
Mouse
The PD-1 and PD-L1 Dual Humanized mouse model expresses only the hPD-1 and hPD-L1 gene sequences. The full humanized PD-1 (ASHU-00015) and PD-L1 (ASHU-00062) mice were used for breeding the dual PD-1 and PD-L1 mice. This mouse model does not express mPd-1 and mPd-L1.
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Strain Information
  • Catalog Number ASHU-00100
  • Model Name PD-1 & PD-L1
  • Strain Name C57BL/6J - Pdcd1em1(hPDCD1) Cd274em1(hPD - L1)/Asc
  • Mutation Type Humanization
  • GENE Synonyms AW495831
  • Human Orthologs CD19
  • Emsamble ID ENSMUSG00000030724
  • MGI ID 88319
  • NCBI ID 12478
  • Backgound C57BL/6J
  • Coat Color Black
  • Mutation Type Humanization
Description

The PD-1 and PD-L1 Dual Humanized mouse model expresses only the hPD-1 and hPD-L1 gene sequences. The full humanized PD-1 (ASHU-00015) and PD-L1 (ASHU-00062) mice were used for breeding the dual PD-1 and PD-L1 mice. This mouse model does not express mPd-1 and mPd-L1.


Research Application
Immunotherapy
Availability
Mouse
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