SIRPA (2) & CD47 & PD-1

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Strain Information

  • Catalog Number ASHU-2000090
  • Model Name SIRPA (2) & CD47 & PD-1
  • Strain Name C57BL/6 - Sirpatm2(hSIRPA)Cd47em1(hCD47) Pdcd1em1(hPDCD1)/Asc
  • Mutation Type Humanized
  • GENE Synonyms Bit, P84, SIRP, SHP-1, CD172a, Ptpns1, SHPS-1, AI835480, IAP, Itgp, Ly101
  • Human Orthologs SIRPA, CD47, PDCD1
  • Emsamble ID ENSMUSG00000037902, ENSMUSG00000055447, ENSMUSG00000026285
  • MGI ID 108563, 96617, 104879
  • NCBI ID 19261, 16423, 18566
  • Background C57BL/6
  • Coat Color Black
  • Mutation Type Humanized
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  • Description
  • Research Application
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This SIRPA,CD47 and PD-1 triple Knock-in strain is established by crossing hSIRPA, hCD47 and hPD-1 mice of three humanized strains together. These triple Knock-in mouse models can be useful for evaluating the efficacy of potential immunotherapy drug combinations