iPSC-based CNS Drug Efficacy and Neurotoxicity Testing

Neurotoxicity Drug Screening: Key Features; Available Test Battery  Page 1
Application Notes: Using available neurons and astrocytes from reporter iPSC lines and control lines  Page 2

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iPSC-derived Neuronal Lineage Cells

Astrocytes Download PDF

Dopamine Neurons Download PDF

Mixed Neurons Download PDF


ONCOREF™ MAPK Mutation Series (EGFR, KRAS, BRAF): 

Isogenic FFPE Slides, Scrolls, and Cell Blocks                                                                                   Page 1
MAPK Reference Standard Series: panel of 51 mutations in EGFR, KRAS and BRAF                              Page 2
Custom Services: custom isogenic cell line generation, custom FFPe services Page 3
Custom Reference Standard Services Page 4

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Genome Editing for Cell Line Model Generation: 

List of cell lines engineered by ASC for clients                                                                                                          Page1
CRISPR/Cas9 Knock-in, Knockout Cell Line Model Generation Service (with case studies) Page 2
CRISPR/Cas9 Blood Lineage Cell Line Gene Editing Service (with case studies) Page 3-4
CRISPR-Cas9 Expressing cell Lines Page 4
TARGATT™ Fast & Specific Knock-in Cell Model Generation Service Page 4
CRISPRCLEAR™ Cell Line Editing Kits Page 5
ONCOREF™ Reference Standards: MAPK Mutation Series (EGFR, KRAS and BRAF) Page 6

Other Custom Services: Custom FFPE Service, Custom Virus Packaging Service,

Cell Line Immortalization Service, and Vector Design and Cloning Service

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Primary Cell Lines Page 8

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iPSC Generation, Disease Modeling, Mutation Correction and Differentiation:

Footprint-free iPSC Generation Service                                                                                                         Page1
CRISPR/Cas9 iPSC Genome Editing/ Disease Modeling Service (with case studies) Page 2-3
CRISPRCLEAR™ Do-It-Yourself Kits for iPSC Editing Page 3
iPSC Characterization Services: Teratoma, pluripotency markers, qPCR, RNA-seq, karyotyping Page 4
iPSC Differentiation Service: cardiomyocytes, hematopoietic lineage cells, hepatocytes Page 5
Neural Stem Cell and Neural Cells Differentiation Service Page 5
Differentiated Neural Stem Cells, Neurons, Astrocytes Page 6
Off-Shelf iPSC and Related Cell Lines: control, patient, gene edited iPSCs and differentiated lines Page 6
Neurotoxicity Drug Screening Service Page 7
iPSC Cell Culture Products: MEF cells, cell culture media, iPSC generation kits, primary cells, FBS, 3D culture media Page 8
iPSC and Differentiated Cell Culture Medium and Kits Page 8

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Genome Engineering of Mouse and Rat Models: 

ASC's Genome Editing Technologies Overview                                                                                           Page1
CRISPR-Cas9 Mouse Model Generation Service (with case studies) Page 2-3
TARGATT™ Fast & Site-specific Knock-in Mouse Service (with case studies) Page 4-5
TARGATT™ Knock-in Mouse Do-it-yourself Products Page 5
CRISPR-Cas9 Rat Model Generation Service (with case studies) Page 6
BAC Knock-in Mouse/Rat Models (with case studies) Page 7

Products for CDX/ PDX Model Research:

  • Autobioluminescent Cell Lines
  • Custom autobioluminescent cell line development
Page 8

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Custom Lentivirus & Retrovirus Packaging Service:

Custom engineering of high quality, high titer recombinant viruses to target a variety of host cells                                                     

Page1    

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