Humanized Gene Knock-in Strategy
Validation Data
Figure 1. The expression of human CD3E in the peripheral blood cells derived from heterozygous or homozygous humanized mice was confirmed by FACS.
Figure 2. Detection of T cell subsets in the peripheral blood cells derived from heterozygous or homozygous CD3E humanized mice.
Figure 3. Detection of B and NK cells in the peripheral blood cells derived from heterozygous or homozygous CD3E humanized mice.
Figure 4. In vitro T cell activation with heterozygous or homozygous CD3E humanized mice.