CD47 - Immune Checkpoint Mouse Models - Mouse Repository - Animal Models - Research

SKU :
ASHU-00050
Catalog # :
ASHU-00050
Availability :
Mouse
Humanized Strategy Validation of Humanized CD47 Expression by FACS Figure 1. Detection of CD47 expression in live cells from lung, brain and spleen of humanized CD47 mice. The FACS results showed that the high expression of humanized CD47 was detected in the live cells from lung, brain and spleen of Homozygous humanized CD47 mice.
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Strain Information
  • Catalog Number ASHU-00050
  • Model Name CD47
  • Strain Name C57BL/6J - Cd47em1(hCD47)Asc
  • Mutation Type Humanization
  • GENE Synonyms IAP, Itgp
  • Human Orthologs CD47
  • Emsamble ID ENSMUSG00000055447
  • MGI ID 96617
  • NCBI ID 16423
  • Backgound C57BL/6J
  • Coat Color Black
  • Mutation Type Humanization
Description

Humanized Strategy

Landingpage-ASHU-00050-CD47-HU-ICPMouse-1

Validation of Humanized CD47 Expression by FACS

Landingpage-ASHU-00050-CD47-HU-ICPMouse-2

Figure 1. Detection of CD47 expression in live cells from lung, brain and spleen of humanized CD47 mice.

The FACS results showed that the high expression of humanized CD47 was detected in the live cells from lung, brain and spleen of Homozygous humanized CD47 mice.

Research Application
Immunotherapy
Availability
Mouse
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