CD2

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Strain Information

  • Catalog Number ASHU-204986
  • Model Name CD2
  • Strain Name C57BL/6-Cd2tm1(hCD2)/Asc
  • Mutation Type Humanized
  • GENE Synonyms Ly37, LFA-2, Ly-37
  • Human Orthologs CD2
  • Emsamble ID ENSMUSG00000027863
  • MGI ID 88320
  • NCBI ID 12481
  • Background C57BL/6
  • Coat Color Black
  • Mutation Type Humanized
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ASHU-204986
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ASHU-204986
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  • Description
  • Related Products

The endogenous mice Cd2 gene was replaced by human CD2 gene.

Validation Data

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Figure1. Detection of CD2 expression in thymus and spleen by RT-PCR. Wild type: only one band at 432 bp with primers F1/R1 (mCd2); Heterozygous: one band at 432 bp with primers F1/R1 (mCd2) and one band at 228 bp with primers F2/R2 (hCD2); Abbr. M, DNA marker; HO, homozygous; HE, heterozygous; WT, wild type.

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Figure 2. Detection of hCD2 expression on Jurkat cell line.

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Figure 3. Detection of hCD2 expression on T cells in Blood in hCD2 KI mice.

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Figure 4. Detection of hCD2 expression on T cells in Spleen in hCD2 KI mice.

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Figure 5. Detection of hCD2 expression on B cells in hCD2 KI mice.

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Figure 6. Detection of hCD2 expression on NK cells in hCD2 KI mice.

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